Bioassay Design, Development, Analysis, Validation, and Monitoring
This course will emphasize the statistical concepts needed for bioassays. Key ideas will be illustrated with useful and relevant examples. Other examples will illustrate how these statistical concepts give insight into the properties of bioassays and how these ideas and properties inform the choices we make in bioassay development, bioassay design, validation, and monitoring. Examples (mostly from cell-based bioassays, some using robotics) will illustrate strategic ways to design bioassays that are practical in the lab and statistically sound. A modular approach to assay design supports use of design of experiments (DOE), easy tuning of assay size to achieve different performance targets for different intended uses, facilitates monitoring, and helps standardize many elements of bioassay design across different assay systems. Examples will highlight how DOE strategies change through bioassay development, when measuring the capability of a bioassay, when demonstrating robustness, when improving an existing bioassay, and when doing validation. We will cover ways that these strategic assay design considerations, when combined with good assay analysis methods, also support good assay monitoring with graphical and quantitative tools as part of a lifecycle approach.
Live Online Academies
Gain real-time access to a subject matter expert delivering online training in a structured virtual classroom environment. Live online academies are virtual versions of some of our most popular face-to-face courses.
Over 2 days students will learn through:
- Live interactive sessions
- Direct interaction with the trainer during live sessions
- Participation in interactive features within sessions including polls, Q&A, break out rooms, tasks, case studies, and more
- Revisiting recorded sessions with unlimited access for 30 days
- Interaction with peers during live sessions and through the online forum
Timings and dates are subject to change - final confirmation will be provided with login details. Delegates will receive login instructions within a week of the course start date. If you have any questions please contact firstname.lastname@example.org.
What will you learn?
How common methods in bioassay labs produce statistically complex designs. How to recognize and describe these designs. How to design bioassays that are practical to perform and statistically sound. Using DoE in bioassays.
Strategies for managing outliers in bioassays and dealing with non-constant variation in bioassay data.
Setting Product Specifications
Looking at clinical experience, manufacturing experience and assay and process capability.
Selected tools for strategic thinking about bioassay: e.g.; throughput, total error, sources of bias.
How to take practical steps towards a lifecycle approach to bioassay management.
Who is this course for?
Those who are involved with the design, development, analysis, validation, monitoring, transfer, updating, and management of biological assays will benefit from this course. This includes bench scientists, assay managers, those responsible for planning and analyzing bioassay validation experiments, statisticians who are new to bioassay, as well as senior and upper level managers who have responsibility for bioassay development and validation.
Delegates of our live online academies said...
would attend another live online academy
found the course beneficial to their day to day role
would recommend the course to others
Engaging in Continuing Professional Development ensures that both academic and practical qualifications do not become out-dated or obsolete; allowing individuals to continually ‘up skill’ or ‘re-skill’ themselves, regardless of occupation, age or educational level. This course has been assessed and is CPD certified.