JOIN LAKEPHARMA AT ANTIBODY DISCOVERY, SELECTION AND SCREENING DIGITAL WEEK 2021
A global free-to-attend 3-day webcast series including 7 webcasts and downloadable resources addressing some of the biggest challenges being faced across the antibody industry at present.
Leveraging the Immunologic Diversity of PentaMice® for COVID-19 Antibody Discovery and Vaccine Development
10:00am EDT / 3:00pm BST / 4:00pm CEST
PentaMice™ comprise 5 strains of genetically and immunologically diverse mice that express 42 distinct MHC class II heterodimers (vs. the single IAαbAβb heterodimer utilized by C57Bl/6 mice). We will discuss our success in using PentaMice (vs. a single inbred mouse strain) to discover SARS-CoV-2 spike protein antibodies and to help identify COVID-19 vaccines with efficacy across a wide range of genetic backgrounds that is more representative of human immunological diversity.