Anja Lux, Ph.D.Postdoctoral Researcher at University of Erlangen-Nuremberg, Germany
Anja Lux obtained her PhD in immunology at the Department of Biology of the Friedrich-Alexander-University Erlangen-Nuremberg in 2010. She has than continued to become a principal investigator at the Chair of Genetics with a research focus on characterization of effector functions of immunoglobulin G (IgG) antibodies. She is especially interested in studying the impact of IgG subclass and glycosylation on interaction with FcgRs and triggering of the complement cascade. She studies these questions both ex vivo using primary cells as well as in vivo employing different mouse and especially humanized mouse models, which are characterized by a full and functional human immune system due to human hematopoietic stem cell transfer in immunodeficient mice. In these mouse models she primarly investigates the therapeutic potential of IgG and its contribution in autoimmunity and chronic inflammation.