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Friedrich Koch-Nolte, PhD
Professor of Immunology and Molecular Biology at University Medical Center Hamburg-Eppend


Friedrich Koch-Nolte is professor of Immunology and Molecular Biology at the University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Work in his lab focuses on extracellular nucleotides as danger signals for cells of the immune system and on the ecto-enzymes and receptors that respond to these nucleotides. His group engineers nanobodies as tools to modulate the function of enzymes and ion channels, as tools to target AAV vectors to specific cells, and as anti-tumor therapeutics. The Koch-Nolte lab has generated transgenic mice that produce affinity matured, soluble nanobody-based heavy chain antibodies.

Agenda Sessions

  • Avidity Engineering of Membrane Protein-specific Nanobody-based Human Heavy Chain Antibodies

    On Demand
  • Exploiting and Understanding Avidity Engineering of Antibodies