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Delivered as a Hybrid Event from December 12 - 16, 2021
Live In-Person Experience Delivered December 12 - 16 2021Marriott Marquis San Diego

Bradley Maron, M.D.
Associate Professor of Medicine at Harvard Medical School

Profile

Dr. Bradley Maron is an Associate Professor of Medicine at Harvard Medical School, Associate Physician in the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, and Co-director of the Pulmonary Vascular Disease Center at the Boston VA Healthcare System. His laboratory focus involves utilizing network medicine and systems biology to characterize the pathobiological mechanisms underpinning complex cardiovascular disease. Through these approaches, Dr. Maron identified a critical cysteinyl thiol redox switch as well as a pro-thrombotic peptide in the CAS protein NEDD9 that regulate pulmonary vascular fibrosis and thrombosis, respectively. These molecular targets have emerged as potentially modifiable small molecule and antibody technologies. In collaborative work, he lead international projects focusing on the hemodynamic spectrum of clinical risk in pulmonary hypertension, which has provided new insight on pulmonary artery pressure and pulmonary vascular resistance levels that associate with adverse clinical outcome. More recently, he has applied network medicine to individualizing the pathobiology of patients with hypertrophic cardiomyopathy. Dr. Maron has co-authored numerous scientific manuscripts, is the co-inventor of several patents or pending patents, and is funded by the National Institutes of Health, American Heart Association, Cardiovascular Medical Research and Education Foundation, Scleroderma Foundation, and the Boston Biomedical Innovation Center (B-BIC). He is a member of the American Society of Clinical Investigation, and a recipient of the distinguished Eleanor and Miles Shore Scholar in Medicine, McKenzie Family Master Clinician, and Harvard Medical School Excellence in Teaching Awards.

Agenda Sessions

  • Targeting NEDD9 to Inhibit Platelet-endothelial Adhesion and Pulmonary Thrombosis

    1:30pm