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Antibody Engineering & Therapeutics US
December 13 - 16, 2023
Marriott Marquis San DiegoLive In-Person Event: December 13 - 16, 2023

Karl Dane Wittrup, Ph.D.
C.P. Dubbs Professor in Chemical Engineering and Biological Engineering at Massachusetts Institute of Technology


Dane Wittrup is the Carbon P. Dubbs Professor of Chemical Engineering and Biological Engineering at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology. Wittrup’s research program is focused on engineering of biopharmaceutical proteins by directed evolution, and development of pharmacological design principles for immunotherapies for cancer. His lab invented yeast display, and formulated a predictive PK theory for tumor targeting agents. He has trained approximately 20 individuals that hold faculty positions around the world. He coauthored a comprehensive textbook on kinetic analyses in biological systems, titled “Quantitative Fundamentals in Molecular and Cellular Bioengineering.” In 2007, he co-founded Adimab, Inc. with Tillman Gerngross, and served in the Office of the CSO for ten years. Particular recognitions of Wittrup’s accomplishments include the AIChE Colburn Award and induction into the National Academy of Engineering.

Agenda Sessions

  • Affinity/Efficacy Relationships for Different Antibody Modalities

  • Co-Chairs’ Remarks