Paul Carter, PhDGenentech Fellow, Department of Antibody Engineering at Genentech, Inc.
Paul is a Genentech Fellow in the Department of Antibody Engineering at Genentech, Inc. His passion is the pursuit of breakthrough antibody-based therapeutics that transform the lives of patients. He is a co-inventor of antibody humanization technology at Genentech that has been utilized for 9+ approved antibody products used to treat millions of patients worldwide. He is also a co-inventor of “knobs-into-holes” technology used to create 5+ bispecific antibodies and a one-armed antibody that have entered clinical development. He invented technology for high-level antibody fragment expression in E. coli that has been used for at least one commercial product. He is an inventor or co-inventor on 48+ issued US patents and 59+ published US patent applications. He has published 117+ scientific articles that together have been cited 19,800+ times (h-index 62). He received a BA in Natural Sciences from Cambridge University in 1982 and his PhD in 1986 under Sir Gregory Winter at the MRC Laboratory of Molecular Biology in Cambridge. From 1986-1989 he was a Postdoctoral Fellow with Dr. Jim Wells at Genentech. He has 30+ years of biotechnology experience: Genentech (1986-2000 and 2010-present), Immunex/Amgen (2000-2003), Seattle Genetics (2003-2008) and VLST (2008-2009). He headed the postdoctoral programs at Genentech (1998-2000), Immunex (2001-2002) and Amgen (2002-2003).