Shane Crotty, Ph.D.Professor, Center for Infectious Disease and Vaccine at La Jolla Institute for Immunology
Shane Crotty graduated from MIT and then obtained his Ph.D. at the University of California, San Francisco, USA in 2001. He carried out postdoctoral studies at Emory University, USA, with Rafi Ahmed before starting his laboratory at the La Jolla Institute for Allergy & Immunology (now the La Jolla Institute for Immunology, LJI), USA, in 2003, where he is now a full professor.
Dr. Crotty’s lab studies the fundamental immunology underlying vaccine functions. Initially trained in molecular virology and then viral immunology, Crotty’s laboratory is best known for understanding T follicular helper (Tfh) CD4 T cells and their critical role in antibody responses (Science 2009, Immunity 2019). The Crotty lab also has made important contributions to viral immunology including SARS-CoV-2 (Cell 2020, Science 2021), B cell immunodominance (Science 2016, Immunity 2018), and the central roles of germinal centers and memory in vaccine immunology (Cell 2019, Nature Medicine 2020). Dr. Crotty was a Pew Scholar and has been a Highly Cited Researcher five years running (2016-2020). His recent COVID-19 immunology work with Alessandro Sette has become the highest public attention getting Cell paper ever (Cell 2020). His study on COVID-19 immune memory (Science 2021) was the largest every study of adaptive immune memory (CD4 T cells, CD8 T cells, antibodies, and memory B cells) for any viral infection, and was covered by the New York Times and other major media outlets.