Theodore Roth

MD/PhD Student at UCSF, USA

Theo Roth is a co-founder of Arsenal Biosciences and was Arsenal’s founding CSO. He is currently completing clinical training in the UCSF MD/PhD program. He has considerable experience in immunology and microscopy through a predoctoral fellowship at the NIH, and in biomedical informatics and systems biology through his undergraduate and masters work at Stanford University. During his PhD at UCSF, he developed non-viral genome targeting, a new efficient method for large scale genetic engineering of primary human immune cells without the need for complex viral vectors. He further developed robust methods of pooled knock-in screening, enabling rapid discovery of synthetic sequences to re-wire T cell genomes. This work has led to pre-clinical development of novel cell therapies for both autoimmune disease and solid tumors.