Thazha P. Prakash, Ph.D.

Executive Research Fellow at Ionis Pharmaceuticals

Executive Director of Medicinal Chemistry at Ionis Pharmaceuticals Inc. Co-inventor of LICA technology for antisense therapeutics. Involved in development of Gen 2 and Gen 2.5 chemistries for antisense drugs and led Ionis ss-siRNA and siRNA programs. Developed simplified synthetic RNA for CRISPR based genome editing. Contributed to early research on discovery of anti HCV drugs. Ph. D. in Organic Chemistry from University of Pune, Pune, India. Postdoctoral training at the University of California, Riverside, California and at the Ionis Pharmaceuticals, Carlsbad, California. Listed as co-author/co-inventor on more than 225 peer-reviewed publications, issued patents and patent applications.