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Yige Wu
Scientist II - Vector Process Development at Bluebird Bio


Chromatography is one of the most expensive steps in the manufacturing process of lentiviral vector (LVV) due to the cost of resins. High-throughput (HTP) method was employed to evaluate a series of candidate resins at various conditions as possible replacement to reduce cost and improve LVV recovery. HTP analytical methods are also developed to accommodate the large number of samples.

Agenda Sessions

  • A High Throughput Process for the Generation of Bispecific Antibodies/ High-throughput Method in Process Development of Lentiviral Vector