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Yige Wu
Scientist II - Vector Process Development at Bluebird Bio


Chromatography is one of the most expensive steps in the manufacturing process of lentiviral vector (LVV) due to the cost of resins. High-throughput (HTP) method was employed to evaluate a series of candidate resins at various conditions as possible replacement to reduce cost and improve LVV recovery. HTP analytical methods are also developed to accommodate the large number of samples.