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Mégane Denu
R&D Engineer Bioproduction at Polyplus-transfection

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Transient transfection of suspension cells is the most commonly used production platform for AAV manufacturing. However, this method shows some limitations in large scale bioreactors: inadequate transfection protocol, reduced transfection efficiency and lower productivity. To address this concern, we present data on the novel transfection reagent showing: i) increased AAV titers, ii) improved transfection protocol for large scale bioreactors and iii) reproducibility of viral titers at different production scale.

Agenda Sessions

  • Next-Generation Transfection Reagent for Large Scale AAV Manufacturing

    11:40