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Thursday, September 24 - EST (Eastern Time, UTC-05:00
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Thursday, September 24 - EST (Eastern Time, UTC-05:00
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Showing 1 of 1 Streams
Business Forum
8:30am - 8:35am
Chair Remarks
8:35am - 8:50am
Innovation Presentation: Pioneering taRNA Therapies for Infectious Disease and Beyond
- Cory Sago - CEO, Amplitude Therapeutics
8:50am - 9:05am
Innovation Presentation: Pioneering brain-specific delivery of antibody-oligo conjugates to treat neurological diseases
- David Hardwicke - Co-Founder, Aerska
9:05am - 9:20am
Innovation Presentation: Exploring First-In-Class Re-Dosable circRNA For Rare Metabolic Disease
- Bakhtyar Ali - CEO, Amrixa Pharmaceuticals
9:20am - 9:35am
Innovation Presentation Opportunity Available
Please contact Jennifer Wickett for more information: Jennifer.Wickett@informa.com
9:35am - 9:50am
The Nanoprimer Platform: Unlocking Extrahepatic Delivery of RNA-based Therapeutics
- RNA-based therapeutics and other advanced modalities are often limited by rapid hepatic uptake and clearance, reducing systemic bioavailability, restricting delivery beyond the liver, and contributing to liver-associated toxicity. These delivery barriers can constrain dose, efficacy, and therapeutic window.
- Nanobiotix’s Nanoprimer is a biocompatible, engineered liposome platform designed to transiently occupy cells of the mononuclear phagocyte system involved in hepatic clearance. Administered shortly before the therapeutic agent, Nanoprimer is designed to reduce liver elimination during the agent’s critical window of activity, increasing systemic exposure and improving the opportunity for target-tissue delivery.
- Multiple preclinical proof-of-concept studies have been demonstrated across modalities, including nucleic acid-LNPs, liposomes, oncolytic viruses, and recombinant proteins. By decreasing liver clearance, Nanoprimer has shown the potential to enhance efficacy, improve extrahepatic exposure, and reduce hepatotoxicity for therapies whose performance is limited by rapid hepatic uptake.
9:50am - 10:15am
Innovation Presentation Opportunity Available
Please contact Jennifer Wickett for more information: Jennifer.Wickett@informa.com
Showing 1 of 1 Streams
Business Forum
11:00am - 12:55pm
Investor Insights: Question Circle
An open Q&A session offering attendees the opportunity to engage directly with leading investors, gain insights into funding strategies, market trends, and what drives investment decisions in the RNA therapeutics space.
- Soyoung Park - General Partner, 1004 Venture Partners
Showing 1 of 1 Streams
Business Forum
2:05pm - 3:05pm
Pharma Insights Question Circle
An open Q&A session providing attendees the chance to interact with pharma leaders, explore industry perspectives, and discuss strategies for advancing RNA therapeutics from discovery to commercialization.
- Elena Diez Cecilia - Senior Director External Innovation DPDS, Johnson & Johnson
- Shaan Gandhi - VP and Head of Partnerships, PAVE, Pfizer
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