Join Biotage at TIDES Digital Week 2020
Webinar: Breaking Bottlenecks: Adjusting mobile phase modifiers to improve peptide purity with minimal chromatographic method development (June 4 at 12pm EDT)
Recent technological advances enable non-biased screening of tens of millions of peptidic compounds containing natural or non-natural amino acids and frequently secondary chemistries, further expanding the use of peptides in drug discovery campaigns. While many automated synthesis platforms can expedite the follow up synthesis demands, peptide purification often creates a bottleneck, slowing delivery of the final purified compounds for evaluation. High Performance Flash Chromatography (HPFC) is gaining traction within the peptide community as a strategy to reduce the impact of the purification bottleneck, primarily due to the flash column’s larger column loading capacity In today’s presentation, attendees will learn how changes to the mobile phase modifier impact selectivity for the desired peptide, leading to a highly pure sample while minimizing the time committed to chromatographic method development.