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Delivered as Hybrid Event from 15-19 November 2021
Live In-Person Conference Delivered 15-17 NovemberSheraton Airport Brussels, Belgium

Annabelle Biscans, PhD
Associate Principal Scientist - Oligonucleotide Chemistry at AstraZeneca


Annabelle Biscans is an Associate Principal Scientist in the Oligonucleotide Chemistry team at AstraZeneca R&D, Sweden. She has a robust expertise in designing and developing novel chemical modalities to improve oligonucleotide therapeutic delivery. Before joining AstraZeneca, she was a postdoctoral associate at the RNA Therapeutics Institute, USA in Anastasia Khvorova’s lab, one of the pioneers in oligonucleotide therapeutics research. There, she made major contributions to the development of novel chemical platforms for enhancing the delivery and uptake of siRNA therapeutics. She was able to design and identify novel conjugated siRNAs that enable safe, sustainable and robust silencing in various extra-hepatic tissues including muscle, heart, and lung. This crucial discovery allows for the targeting of several new targets for therapeutic intervention and advance the oligonucleotide therapeutics field.

Agenda Sessions

  • Oligonucleotide Conjugation Strategies