Jayaprakash Nair, PhDSenior Director, Chemistry and Delivery Science at Alnylam Pharmaceuticals
Dr. Jayaprakash (Jay) Nair joined Alnylam Pharmaceuticals in 2005 where he currently serves as Senior Director, Chemistry & Delivery Science, Research heading the Medicinal Chemistry group focused on RNAi platform and siRNA delivery. In this role, Dr. Nair has contributed to the development of GalNAc conjugates and lipid nanoparticles, two clinically validated platforms for siRNA delivery, and the advancement of multiple therapeutic programs to development, which culminated in multiple approval of RNAi therapeutics ONPATTROTM, GIVLAARITM and OXLUMO™. He is also currently co-leading RNAi platform delivery efforts with focus to develop extra-hepatic platform for CNS, Ocular, Muscle and Kidney.
Jay received his Ph.D. in Organic Chemistry in 2000 at the National Chemical Laboratory, Pune, India. He moved to the U.S. for his postdoctoral research at North Carolina State University and Natural Product and Glycotechnology Research (NPG) Institute where he worked novel chemistries, oligosaccharide synthesis and characterization.
During Jay’s almost 17 years of experience in the field of oligonucleotide therapeutics, he has contributed to siRNA delivery and advancement of RNAi platform. He is the author of more than 50 peer-reviewed scientific publications, reviews, and inventor on more than 40 issued patents or patent applications.