Addressing Complex Oligonucleotide Therapeutics and Approach Towards Endotoxin Removal

Carter Holt, Process Development Supervisor at Axolabs, discusses the importance of removing endotoxins from biological solutions at the TIDES USA conference in San Diego, Calif. In this interview, Holt highlights the potential points of endotoxin introduction during the manufacturing process and discusses Axolabs’ approaches, including the use of charged filters, SEC chromatography, and ultrafiltration, for efficient endotoxin removal.