Leo James, PhD

MRC Programme Leader at MRC Laboratory of Molecular Biology

Speaker

Leo trained with Prof. Dan Tawfik and Sir Greg Winter before establishing his own lab at the MRC Laboratory of Molecular Biology in Cambridge. Significant work includes the discovery of the cytosolic antibody receptor TRIM21 and dissection of how it prevents infection by intercepting viruses, bacteria and pathogenic proteins inside the cell. Leo has also developed technologies based on his research such as ‘TrimAway’, a technique which exploits TRIM21 for the rapid and specific degradation of cellular proteins.