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Delivery of Macromolecules
June 8, 2022
Digital Event8:00AM EST // 1:00PM BST // 2:00PM CEST
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Delivery of Macromolecules - ET (Eastern Time, GMT-05:00)

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Delivery of Macromolecules - ET (Eastern Time, GMT-05:00)
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Showing 1 of 1 Streams
8:00am - 8:10am
Welcoming Remarks
8:10am - 8:40am
Overview - Delivery of RNA Therapeutics: Discovery and Development of Lipidic Nucleic Acids, Lipid Nanoparticles and GalNAc Conjugates
  • Muthiah (Mano) Manoharan - Senior Vice President of Drug Discovery, Alnylam Pharmaceuticals, USA
8:40am - 9:10am
Delivery of RNA Therapeutics by Lipid- and Polymer-Based Nanoparticles
  • Heinrich Haas - Vice President, RNA Formulation & Drug Delivery, BioNTech AG, Germany
9:10am - 9:40am
GalNAc-Mediated Oligo Delivery to the Liver; What Else Can We Learn?
  • Christopher Brown - Director, Oligo Delivery, Korro Bio Inc., USA
9:40am - 10:10am
Development of Molecular Vectors for Targeted Delivery of Therapeutic Oligonucleotides
  • Guillaume Jacquot - Translational Research Manager, Vect-Horus S.A.S., France
10:10am - 10:40am
Delivery of RNA Therapeutics: The Great Endosomal Escape!
  • Satish Jadhav - Post Doctoral Researcher, University of California San Diego, USA
10:40am - 11:00am
Coffee Break & Networking
11:00am - 11:30am
Mechanisms of Transport Across the Blood-Brain Barrier for Delivery of Biologics
  • Exploiting receptor mediated transcytosis for brain delivery
  • Intracellular trafficking across the Blood-Brain Barrier
  • In vitro Blood-Brain Barrier models for new target discovery
  • Roberto Villaseñor Solorio - Principal Scientist, Brain Delivery, Roche, Switzerland
11:30am - 11:50am
Latest Breaking Research and Case Studies: Glutathione-Sensitive Nanogels Encapsulating an Antioxidant Enzyme Reduce oxLDL Uptake by Macrophages in Vitro
  • Rupali Dabas - PhD Candidate, Imperial College London, UK
11:50am - 12:10pm
Latest Breaking Research and Case Studies: Therapeutic MK2 Inhibition Blocks Pathological Vascular Smooth Muscle Cell Phenotype Switch
  • William Tierney - PhD Candidate, Vanderbilt University, USA
12:10pm - 12:30pm
Coffee Break & Networking
12:30pm - 1:00pm
Antibody-cytokine fusions for the Treatment of Cancer and of Chronic Inflammation
  • Developing clinical stage targeted therapeutics
  • Target discovery and development
  • Case study
  • Dario Neri - CEO and CSO, Philogen, Switzerland
1:00pm - 1:20pm
Latest Breaking Research and Case Studies: In-Cell Penetration Selection—Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery
  • Charlotte Farquhar - PhD Candidate, Massachusetts Institute of Technology, USA
1:20pm - 1:50pm
Bioinspired Nanoparticle Mediated Protein Delivery for Targeted Thrombolytic Therapy
  • Innovative fibrinogen-mimicking multiarm nanoparticles including lipid nanovesicles
  • Novel targeted delivery and triggered release of thrombolytic proteins
  • Promising potential for thrombolytic nanomedicines
  • Nikki Henry - PhD Candidate, Imperial College London, UK
1:50pm - 2:50pm
End of Day & Additional Networking on the Platform
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