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Drug Delivery of Oligonucleotides, Peptides, RNA, mRNA and CRISPR - WHITEPAPER

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Research and innovation in drug delivery systems is a rapidly evolving field, especially as the scope of drugs now encompasses not only small molecule drugs but also biological macromolecules including DNA, RNA, proteins and peptides. As a field that has seen fast paced expansion as far as research and development is concerned, it encounters many challenges in terms of development of delivery systems catering to these novel drug entities.

This whitepaper explores the latest innovations, strategies and challenges of drug delivery of oligonucleotides, peptides, RNA, mRNA and CRISPR, including:

  • Novel Technologies for the Delivery of Macromolecular Therapeutics

  • Novel Polymeric Delivery Vehicles

  • mRNA Lipid Nanoparticles

  • Antibody Drug Conjugates (ADCs)

  • Extra-Hepatic Delivery of Oligonucleotides (siRNA and ASOs)

  • RNAi Delivery to Hepatic System

  • RNAi Delivery to Non-hepatic Systems

  • Antibody-Oligonucleotide Conjugates (AOCs)

  • Delivery of siRNA Conjugates

  • Innovations in Peptide Delivery

  • Adhesive Dermally Applied Microarray (ADAM)

  • Peptides as a Delivery Vehicle

  • Delivery of Peptide Therapeutics Inside Cells

  • Strategies for delivery of CRISPR and mRNA


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This piece represents the views of the author and not necessarily the views of Informa Connect Life Sciences or the Antibody Therapeutics and Engineering conference series.

ABOUT THE AUTHOR: Poonam Balani, PhD, is a medical writer covering pharmaceutical and biomedical niche. She has authored whitepapers in regulatory sciences, cell and gene therapies and contributed to medical encyclopedias and editorial summaries.

Have any questions about the report or interested in sponsoring a future whitepaper? Email andrew.burrows@informa.com.

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