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Antibody Engineering

Novel technologies and approaches for optimizing antibody discovery - WHITEPAPER


WHITEPAPER: Novel technologies and approaches for optimizing antibody discovery

Successful antibody discovery has been dependent on the proper identification of a target and the mechanisms of action associated to the development of a specific disease. But, this conventional wisdom of the antibody development roadmap is being challenged, by how long it takes from target research to the initiation of a clinical program. As the search for validated targets becomes more challenging, unconventional strategies, such as phenotypic screening, are becoming more significant.

This whitepaper examines the latest innovations addressing the current practical challenges in antibody discovery, including:

  • Phenotypic screening and 'function-first' approaches

  • Next generation sequencing and its challenges

  • Bioinformatics tools for antibody optimization

  • Machine learning techniques for target deconvolution

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