Jun 15

Sensors and Sensor Tech in ManufacturingWednesday, 15 June 2022 - ET (Eastern Time, GMT-05:00)

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Sensors and Sensors Tech in Manufacturing

8:00am - 8:15am

Introductory Remarks

Introducing the conference

8:15am - 8:45am

Overcoming hurdles of process analytical technologies in bioprocess manufacturing

Keynote

Evolution of sensors for bioprocesses
PAT for bioprocesses
- Benefits of using PAT in bioprocesses manufacturing
- Continuous processing
Specific technologies and sensors currently used, based on e.g. probes, instruments
Implementing PAT tomorrow
- Emerging solutions such as miniaturization

Véronique Chotteau - Director of Advanced BioProduction & Principal Investigator of CETEG Cell Technology, VINNOVA Competence Centre for Advanced BioProduction by Continuous Processing, Sweden

8:45am - 9:15am

Implementing PAT for control of continuous downstream processing of mAbs

Novel cross Analytical Technology sensors for downstream processes
Single use sensors for MABs
Combining traditional and newer single uses sensor technologies for MAB production
RAMAN probes to improve sensor ability detect molecular variants

Garima Thakur - Doctoral Researcher, Indian Institute of Technology Delhi (IITD), India

9:15am - 9:45am

Wellness Break and Refreshments

9:45am - 10:15am

How using analytical tools to understand organisms will benefit analytical technologies in manufacturing

Application of Fluorescent nanosensors to improve cell and gene therapy manufacturing.
Cell and biotherapeutics manufactured using bioreactors perform extracellular measurements of key biological parameters such as pH Oxygen and Temperature.
However, the majority of important biological changes occur subcellularly for which there is limited data and shortfall in available analytical tools.
The team at the University of Nottingham have development nanometre sized probes to characterise subcellular pH Oxygen and Temperature
This exciting new data could provide researchers with additional information that could enhance the efficiency cell and gene therapy manufacture.

Veeren Chauhan - Nottingham Research Fellow in Whole Organism Analytics, University of Nottingham, UK

10:15am - 10:45am

How sensor technology is utilized within emerging cell therapies

Importance of having accurate sensors during a cell therapy manufacturing process
How sensor technology is currently used in allogeneic cell therapy platforms
How sensor technology can evolve and improve to support cell therapy manufacturing

Schuyler Gardner - Sr. Associate Engineer, Century Therapeutics, USA

10:45am - 11:15am

Wellness, Refreshments and Lunch

11:15am - 11:45am

Technology evaluation and Multi-modal AI/ML capabilities for supporting early Drug Discovery

How does AI/ML provide data to support early therapeutic discovery and manufacturing
Industry 4.0 with emphasis on digital twins, process modelling and AI/ML
Merging Insilco technologies for drug discovery
Evaluations of New AI/ML and communication in different fora

Christos Varsakelis - Associate Director Artificial Intelligence/Machine Learning, The Janssen Pharmaceutical Companies of Johnson & Johnson, Belgium

11:45am - 12:15pm

How You Can Leverage Emerging Technologies to Optimize Manufacturing Bioprocesses

We will increase audience awareness of the problems and challenges, as well as solutions, connected to the introduction, adoption and deployment into production of some promising emerging digital technologies that greatly benefit from sensor data. The main topics of discussion will be the following:

How sensors and emerging technologies could evolve together in the next 3 to 5 years
Truths and misconceptions on how to optimize pharma bioprocesses with AI and ML
How you can leverage Virtual and Augmented Reality capabilities to generate cost savings

Fausto Artico - Global R&D Tech Head and Director of Innovation and Data Science, GSK, UK