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Daniel Obrecht, Ph.D.
Chief Scientific Officer, Co-Founder at Polyphor Ltd.


After a PhD in organic chemistry obtained from the University of Zurich (1983), D. Obrecht spent two years of postdoctoral studies working in Prof. R. E. Ireland’s group at the California Institute of Technology on the total synthesis of avermectin. He then joined the Central Research Laboratories of F. Hoffmann-La Roche in Basle (1985), where he worked on several drug discovery projects. In 1989 he started a project with the aim to find small molecule peptidomimetics of exposed protein epitopes. In 1993 he was awarded Roche Lecturer, and in 1994 he headed the combinatorial chemistry project at Roche Basle. End of 1996 he co-founded Polyphor with his brother Dr. Jean-Pierre Obrecht. The main expertise of D. Obrecht are synthetic organic chemistry with particular emphasis on macrocycles, medicinal chemistry and drug discovery. He is currently CSO at Polyphor and the author and co-author of 68 publications and 35 patents, including key patents on the Protein Epitope Mimetics (PEM) Technology and products, such as POL6014, POL7080, and POL6326.