The Medicine Maker is a publication focusing on manufacturing and development in the pharmaceutical and bio pharmaceutical industry. With CAR-Ts approved in both the US and the EU, the advanced therapies field is answering the scientific questions of efficacy and safety – cell and gene therapies are becoming therapeutic realities. But new challenges are emerging... How can manufacturing become more closed and automated to reduce the risks associated with human intervention and manual operations? How does the field overcome the problem of handling living breathing cells in transit? And are healthcare systems ready for cell and gene therapies?