Jason Rouse, Ph.D.

Senior Director at Pfizer, Inc.

Speaker

Jason Rouse manages the Mass Spectrometry and Biophysical Characterization (MSBC) laboratory at Pfizer, Inc., which is a sub-group of the large molecule, Analytical Research and Development department in the greater Biotherapeutics Pharmaceutical Sciences process and product development organization. MSBC works collaboratively with research, development, and manufacturing groups across Pfizer to carry out product characterization and comparability exercises, as well as time-sensitive investigations and bioprocess support. Jason received his Ph.D. degree in Analytical Chemistry from Michigan State University in 1993 and joined Genetics Institute (GI) as a post-doctoral research fellow. Jason was promoted into positions of greater responsibility over the years in GI, Wyeth, and Pfizer, and currently he is the director of the MSBC group.

Jason’s scientific interests include the elucidation of released N- and O-linked glycan structures, the characterization of intact glycoprotein therapeutics by ultrahigh-resolution MS approaches, and the development of in-silico prediction software for deamidation, isomerization and oxidation hotspots.