Rowshon Alam, PhD

Vice President, Head of Chemistry at Prime Medicine

Speaker

Dr. Rowshon Alam is Vice President, Head of Chemistry, where he leads the group for chemical synthesis, process optimization, scale up, and in-process analytics of long guide RNA to support pre-clinical development of various in vivo programs. Prior to Prime medicine, Rowshon worked at Wave Life Sciences for 6 years (director, process development), Nitto Denko Avecia for 5 years (group leader, process dev.) and at Alnylam for approx. 2 years (scientist, medicinal chemistry) to develop scalable process for stereo-defined oligonucleotides, siRNA, ASO with a variety of chemical modifications and ASO/siRNA conjugates with delivery ligands.

Rowshon obtained his PhD in 2000 in pharmaceutical chemistry from Kyushu University (Japan) followed by JSPS fellowship & JST, CREST fellow (2000-2003). Rowshon was a recipient of NIH fellowship at National Institutes of Health (2003-2006) where he developed triplex forming oligonucleotides (TFO) as a gene targeting reagents. He then worked as a Research Assistant Professor at the University of North Carolina at Chapel Hill (UNC-CH) for chemical synthesis of highly chemically modified ASO and ASO-conjugates (2006-2009). Rowshon was authored >20 peer-reviewed publications in the field of oligonucleotide research.