Seb Caille, PhD

Senior Director at Avidity Biosciences

Speaker

Seb is the Senior Director of Oligonucleotide Development at Avidity Biosciences, where he leads a team focused on development, characterization, and validation of processes to manufacture late-stage assets such as Del-desiran, Del-brax, and Del-zota. Prior to joining Avidity, Seb was a Scientific Director at Amgen, where he led teams managing the development of processes to prepare small molecules, oligonucleotides, glycosides, and peptides, in all phases of CMC development. His teams delivered processes for the manufacture of Omecamtiv Mecarbil, Sotorasib, and Olpasiran. Seb is the author of forty-seven refereed publications throughout his career and the recipient of an ACS Mid-Career Investigator Award (2024). Seb is an active member of IQ and EPOC working groups.