The Almac Group has been supplying peptides to the research community and for clinical trials for over 20 years. Over that period, we have developed a high level of technical expertise which allows us to manufacture peptides with a wide range of complexity. Our service offering includes:• High-throughput manufacture of peptides for pre-clinical research needs up to g scale• Expertise in process development as projects transition from research to GMP manufacture• GMP-certified manufacture facility for scales from g to kg• Experience in the manufacture of long peptides (>100 amino acids)• Significant experience in conjugation of peptides to small molecule therapeutics, entities for half-life extension, and proteins• Significant experience in the manufacture of peptide cocktails for vaccine product • Expert in-house analytical resource for method development, validation, release testing, and ICH stability studies• For oligonucleotide synthesis, Almac offers in-house enzymatic screening of ligases against clients specific target sequence including identification of suitable ligation sites based on Almac’s extensive experience. Almac’s ligase panel has the following attributes

• Activity against both natural and unnatural nucleosides with modifications including 2’ F, 2’MOE & 2’OMe
• Can be provided with low-endotoxin levels on request
• The enzymes can be used to complement existing oligonucleotide synthesis by combining a biocatalytic approach with existing classical chemical synthesis
• Delivery of high quality RNA product with low impurity profile

Our technical expertise, coupled with our approach to customer care and project management, make Almac an excellent partner for peptide manufacture. Think Almac for peptide excellence.