Location: Room 3102

ThromBio (and associated entities) is a clinical stage drug discovery company established to commercialise the scientific discoveries of Founder, Scientific and Medical Officer, Prof. Shaun Jackson (Heart Research Institute), and his collaborator, Prof. Richard Payne (University of Sydney).

Both the Jackson and Payne laboratories are international recognised authorities in the identification and in-vivo characterisation of novel therapeutic products for treatment of thrombotic disorders, with an initial focus on the treatment of Acute Ischemic Stroke (AIS). These discoveries have emanated from their pioneering breakthroughs on the key pathological mechanisms driving arterial thrombus formation, as well as through the discovery of new classes of nature-inspired anticoagulant agents. These exciting antithrombotic drugs have novel mechanisms of action, act synergistically together, and have a wide therapeutic window.

ThromBio has significant experience in progressing small molecule drug candidates from discovery to human trials, with its 'clinical lead', the novel antiplatelet inhibitor TBO-309. TBO-309 has an unprecedented safety profile, and the potential to transform the standard of care for AIS whilst dramatically expanding the potential of acute stroke treatment.

Professor Payne's laboratory has discovered naturally occurring anticoagulants derived from blood-feeding organisms (the saliva of the Australian 'bush tick'), leading to the patented discovery of new anticoagulant agents from two distinct peptide families that cause minimal bleeding, whilst being highly efficacious, therefore serving as potentially highly attractive candidates for use in acute stroke therapy.
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This portfolio of novel anticoagulants potentially allows for a valuable extension of acute treatment windows, and a whole new generation of conjunctive therapies, dramatically improving patient outcomes and health economics worldwide.

Peter BushCEO at ThromBioSpeaker

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Peter Bush
CEO at ThromBio
Speaker