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Starting TBC
LIVE Online Course
Starting TBC

LIVE Online Course

Examine the principles of separation chemistry to develop a robust early downstream process operation for your Biologic

Course Overview

Downstream process operations are essential to ensure you obtain your target biologic in its purest form. Consisting of core sequential steps, it is important to streamline your early downstream process in order to maintain bioprocess efficiency.

On this virtual classroom course, you will consider the best practices for developing an early downstream process considering important issues including; biologic type, separation principles, membrane-process steps, and upstream integration. Additionally, you will also explore core separation technologies including; bio-chromatography, flocculation, crystallization, and pegylation. You will be able to cement your knowledge during interactive case study sessions.

Live Online Academies

Gain real-time access to a subject matter expert delivering online training in a structured virtual classroom environment. Live online academies are virtual versions of some of our most popular face-to-face courses, delivered in bitesize sessions of 1.5-3 hours online.

Over 2 weeks students will learn through:

  • Live interactive bitesize sessions
  • Direct interaction with the trainer during live sessions
  • Participation in interactive features within sessions including polls, Q&A, break out rooms, tasks, case studies, and more
  • Revisiting recorded sessions with unlimited access for 30 days
  • Interaction with peers during live sessions and through the online forum

Timings and dates are subject to change - final confirmation will be provided with login details. Delegates will receive login instructions within a week of the course start date. If you have any questions please contact

What will you learn?

Regulations for DSP

Understand the main objectives of downstream processing and what the regulators expect.

Key reaction steps

Familiarise yourself with key reaction steps in downstream processing such as: redox reactions and pegylation, solubilization, heat treatment and detergent treatment.

Core principles

Explore core underlying principles of bio-chromatography, including interactions between stationary/liquid phases.

Process development

Develop an early downstream process taking into consideration factors such as screening, bio-chromatographic technologies, and scale-up. Consider membrane-based process steps and appreciate the importance of cleaning/testing, optimization, and viral filtration.

Who is this course for?

This course is directly applicable to those who are new to downstream process operations or established downstream process professionals wishing to further their knowledge of new technologies. Likewise, this course is also applicable to those working in upstream who need to understand how to integrate the process. Relevant job departments may include:

  • Downstream Process Development
  • Upstream Process Development
  • Research Scientist
  • Process Development
  • Quality Control

Delegates of our live online academies said...


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25% discount on Routledge books

As a student on the course you will receive a 25% discount on any Routledge books or eBooks. To view the full product range visit the Routledge website

Examples of books and eBooks within biopharmaceuticals include:

  • Bioprocess Engineering: Downstream Processing
  • Bioreactors: Animal Cell Culture Control for Bioprocess Engineering
  • Fundamentals of Modern Bioprocessing
  • Cell Culture Bioprocess Engineering, Second Edition
  • PAT Applied in Biopharmaceutical Process Development and Manufacturing
  • Process Validation in Manufacturing of Biopharmaceuticals
  • And more