Jim WeteringsVice President Research USA, RNA Therapeutics & Delivery at SirnaomicsSpeaker
Profile
Jim has had a tight bond with Oligonucleotides since 2002, performing research on PNA (conjugates) in the van Boom group at Leiden University, the Netherlands and targeted SSO conjugates at Prosensa. During his Ph.D at Leiden University he synthesized and studied CpG Oligonucleotide and other TLR ligand containing conjugates. At Cenix BioScience, he developed targeted siRNA conjugates for CNS delivery. And at Cristal Therapeutics he led various projects on the (targeted) nanomedicine delivery of oligonucleotide in oncology. In 2019 he joined AstraZeneca in Sweden, to further the advancement of (targeted) oligonucleotide therapeutics. Since December 2022, Jimmy joined Sirnaomics in the USA as Senior Director, designing novel oligonucleotide chemistries and targeted version thereof.
Jimmy (co-)authored 13 articles and holds several patents for drug delivery enabling technologies, including the most recent one on TMTHSI, ClicR® exclusively licensed to Synaffix and commercially available for R&D purposes.
Agenda Sessions
Addressing Novel Delivery Tools Needed to Support Next-Gen RNA Therapeutics
, 16:45View SessionOligo-based Therapeutics: Round Tables
, 08:45View Session