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Muthiah (Mano) Manoharan, PhD
Senior Vice President of Drug Discovery at Alnylam Pharmaceuticals, Inc.

Profile

Dr. Muthiah (Mano) Manoharan serves as a Senior Vice President and a Distinguished Research Scientist at Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA. Dr. Manoharan joined Alnylam in 2003. He built the chemistry group at Alnylam and pioneered the discovery and development of RNA interference-based human therapeutics. Dr. Manoharan has had a distinguished career as a world-leading chemist in the areas of oligonucleotide chemical modifications, conjugation chemistry, and delivery platforms (lipid nanoparticles, polymer conjugates, and complex-forming strategies). He is an author of more than 200 publications (nearly 37,000 citations with an h-index of 85 and an i10-index of 329) and over 400 abstracts, as well as the inventor of over 225 issued U.S. patents.

Agenda Sessions

  • Discovery, Preclinical and Clinical Development of Oligonucleotides

    12:15
  • Keynote Introduction by Session Chair and KEYNOTE PRESENTATION with Live Q&A -Antibody-siRNA Conjugates

    14:45
  • Oligonucleotide Conjugation Strategies

    12:15