Seb Caille, PhD

Senior Director at Avidity Biosciences

Speaker

Seb Caille is a Senior Director at Avidity Biosciences, where he leads the Oligonucleotide Process Development team. Seb graduated with his Ph.D. in organic chemistry from the University of British Columbia, and, after a postdoctoral fellowship at UC Irvine, started his career at Amgen in the Synthetics Drug Substance Team. Seb has led teams performing route selection, process development, process characterization, and process validation activities for a diverse set of drug substance targets, including small molecules, oligonucleotides, glycosides, peptides, and bioconjugates. He is the author of forty-seven refereed publications throughout his career and the recipient of an EPA Green Chemistry Challenge Award (Sotorasib – 2022) and ACS Mid-Career Investigator Award (2024). He co-leads the Homogeneity Testing working group of IQ Consortium.