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TIDES Europe: Oligonucleotide and Peptide Therapeutics
12 - 14 Nov 2024
Hamburg, Germany

Theo van Berkel, Ph.D.
Retired Head of Division at Leiden University
Speaker

Profile

Study :

1964-1971 Biochemistry University of Amsterdam

Work:

1971-1974 Pyruvate Kinase isozymes PhD Erasmus University Rotterdam

1974-1986 post doc and assistent Prof. Erasmus University Rotterdam

1986-2011 Full Professor and Head of the Division of Biopharmaceutics Leiden University

2011-….. Emeritus Professor Leiden University

Research:

Exploring endogenous transport routes for the delivery of drugs

Development of lipid nanoparticles reflecting lipoproteins ( so-called neo- lipoproteins)

Receptor studies to obtain high affinity ligands for targeting drugs i.e. the asialoglycoprotein receptor

Mechanistic studies on Atherosclerosis to identify new targets for drug intervention


Outcome

Supervision of 65 PhD theses

More than 450 publications in major journals like: Nature, Nature Medicine, J.Clin.Invest. New England J Med, Lancet, PNAS USA, J Biol Chem, Circulation,Circulation Res , Arteriosclerosis Thromb Vasc Biol.

Agenda Sessions

  • Historical Perspective and Lessons from the Early Days of GalNAc ASOs, Paving the Way for Clinical Application of Nucleotide Medicines

    17:00