Trillium Extracellular Vesicles publishes high-quality research and review articles in the broad field of extracel lular vesicles (EVs). This includes all aspects of extracellular vesicle biology, such as their role in cancer infection, inflam mation and other dispositions. EVs are assembled in cell type specific mechanisms and provide very promising biomarkers for a variety of diseases. They are becoming increasingly relevant in various biological and diagnostic settings, so our topics ranging from clinical applications as disease markers to therapeutic avenues.