Main Conference Day 2Thursday, 27 February 2025

7:45am - 8:10am

Registration and Coffee

8:10am - 8:15am

Chairperson’s Remarks: Plenary Day 2

8:15am - 8:45am

Morning Spotlight Presentation: Isolation and Drying of Peptides and 0ligonucleotides – Improved Production Capacities During Large Scale Manufacturing

Keith Cronce - Chief Operating Officer, Fluid Air, A Division of Spraying Systems

Plenary Session

Showing 1 of 1 Streams

Plenary Session

8:45am - 9:15am

Complete Chemical Synthesis of mRNA for Cancer Vaccine

Hiroshi Abe, PhD - Professor, Department of Chemistry, Graduate School, Nagoya University

9:15am - 9:45am

Developing the Next Generation RSV Vaccine

Dong Shen, MD, PhD - CEO, RNAimmune, Inc.

9:45am - 10:15am

RNA Therapy for Asthma

Thomas Langenickel, MD, PhD - Chief Medical Officer, Ethris GmbH

10:15am - 10:55am

Networking Refreshment Break with Poster and Exhibit Viewing

Concurrent Conference Tracks

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Track 1: Oligonucleotides

Track 2: Peptides

10:55am - 11:00am

Chairperson’s Remarks: Track 1

Sridhar Vaddeboina, Ph.D. - Vice President, Analytical Development, Wave Life Sciences

11:00am - 11:30am

CMC Strategies for the Characterization of Stereopure Platform Chemistry

Sridhar Vaddeboina, Ph.D. - Vice President, Analytical Development, Wave Life Sciences

11:30am - 12:00pm

Template-independent Enzymatic Synthesis of Natural and Fully Modified siRNA Oligonucleotides

Jonathan Rittichier, PhD - Chief Scientific Officer & Co-Founder, EnPlusOne BioSciences

12:00pm - 12:30pm

Synthesis of Nucleic Acid Therapeutics: Next Generation Processes and Solutions

Sirat Sikka - Senior Scientist, Applications and Innovation, Thermo Fisher Scientific

10:55am - 11:00am

Chairperson’s Remarks: Track 2

El Djouhar Rekaï, PhD - Head of Peptide Process Development & Manufacturing, PolyPeptide Group

11:00am - 11:30am

Industry Perspective on the Selection of Regulatory Starting Materials for Synthetic Peptides

John Lopez, PhD - Associate Director Science & Technology, Novartis

11:30am - 12:00pm

Impurities in Peptide Drug Substance and Challenges Faced during Registration (in US, EU, Brazil and China Markets) and Commercial Phase

Dinesh Parmar - Associate Director Regulatory Affairs, PolyPeptide Group

12:00pm - 12:30pm

Statistical Design of Experiments in Peptide Process Development

Alaric Desmarchelier, PhD - Business Development Manager - Peptides, Almac Group

12:30pm - 1:40pm

Networking Luncheon with Poster and Exhibit Viewing

Showing 2 of 2 Streams

Track 1: Oligonucleotides

Track 2: Peptides

1:40pm - 1:45pm

Chairperson’s Remarks: Track 1

Sridhar Vaddeboina, Ph.D. - Vice President, Analytical Development, Wave Life Sciences

1:45pm - 2:15pm

Drug Substance and Drug Product CMC Strategies for Start-Ups and Smaller Companies

Chris Oswald - Founder, Owner, and Principal Consultant, Coswald Consulting LLC

2:15pm - 2:45pm

Oligonucleotide API Quality

2:45pm - 3:15pm

Oligonucleotide Process Validation

1:40pm - 1:45pm

Chairperson’s Remarks: Track 2

1:45pm - 2:15pm

Development of an Efficient and Scalable CSPS Process for a Mid-Sized Cyclic Peptide

Hiroshi Iwamura, PhD - Deputy Head of API Process Development Department, Chugai Pharmaceutical Co., Ltd.

2:15pm - 2:45pm

Overcoming Aggregation Challenges in Peptide Manufacturing: Technical Approach and Case Studies

El Djouhar Rekaï, PhD - Head of Peptide Process Development & Manufacturing, PolyPeptide Group

2:45pm - 3:15pm

An Inline Monitoring Method Integrated Flow Chemistry for Peptide Synthesis and Manufacturing

Pengyu Xu, PhD - President and Representative Director, SynCrest Inc.

3:15pm - 3:45pm

Networking Refreshment Break with Poster and Exhibit Viewing

Showing 2 of 2 Streams

Track 1: Oligonucleotides

Track 2: Peptides

3:45pm - 4:15pm

Development of a Kilogram-Scale Manufacturing Route for Guadecitabine: A Dinucleotide DNA Methyltransferase Inhibitor

Yogesh Sanghvi, PhD - President, Rasayan Inc.

4:15pm - 4:45pm

Analytical Strategies for RNA Therapeutics

4:45pm - 5:15pm

Oligonucleotide Purification and CMC Strategies – Increasing Efficiencies/Overcoming Challenges

Robert Gronke, PhD - Senior Principal Scientist, Technical Development, Biogen, Inc

3:45pm - 4:15pm

GLP-1 Process Development and Manufacturing

4:15pm - 4:45pm

Liquid-phase Peptide Fragment Manufacturing Technologies and Workflows

Adrian Amador, PhD - Director of Process Chemistry, Cambrex

4:45pm - 5:15pm

Late Breaking Presentation

5:15pm - 6:15pm

Networking Cocktail Reception with Poster and Exhibit Viewing

Please join your fellow attendees in the exhibit hall for an evening of networking while enjoying beverages and appetizers.

6:15pm - 6:20pm

Close of Day Two

Main Conference Day 2Thursday, 27 February 2025

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