Redefining Cell Line Engineering for Performance and Stability
In today’s fast-paced biologics landscape, productivity alone is no longer enough. Successful development now demands systems that are stable, predictable, and scalable. Qualities that must be deliberately engineered from the very first stages of cell line design. Without this foresight, late-stage variability and unexpected manufacturing challenges can erode both timelines and confidence in your pipeline.
Kathryn Beal brings a wealth of upstream development expertise from her tenure at Pfizer, where she specialized in optimizing CHO host systems and refining expression vector strategies to drive both high yield and robust performance. Her work focuses on rational vector design and innovative dual site-specific integration systems. Approaches that reinforce consistency across every stage of development and scale-up, from early research to commercial manufacturing.
In her upcoming session, Kathryn will share how strategic planning of expression system architecture can not only accelerate development timelines but also reduce variability and risk in later stages. Attendees will gain actionable insights into:
Engineering strategies that balance productivity with long-term stability – ensuring your cell lines deliver reliable performance across multiple scales.
Designing development platforms with commercial realities in mind – translating early-stage decisions into scalable, manufacturable solutions.
Leveraging analytical data to guide upstream decision-making – using early insights to prevent downstream surprises and optimize overall workflow efficiency.
As biologics programs become increasingly complex and time-to-market pressures intensify, building resilient, scalable cell platforms has emerged as a core driver of competitive advantage. Kathryn’s session offers both a forward-looking vision and immediately applicable strategies for upstream optimization, empowering teams to streamline development while safeguarding quality and consistency.
Don’t miss this opportunity to learn from a leading expert who bridges cutting-edge science with practical, scalable solutions — and discover how thoughtful design today can transform your biologics development tomorrow.