Key Sessions
Mohamed ElSayed
Keynote Presentation: Facilitating APAC Wide and Cross-Broader Collaboration of RNA Medicines – Singapore’s Nucleic Acid Therapeutic Initiative
NATi
keyboard_arrow_right
Search & Filter keyboard_arrow_right
keyboard_arrow_left Hide
Day 1 - UTC+08:00
keyboard_arrow_leftSearch & Filter
search
Streams
Clear
Formats
Day 1 - UTC+08:00
search
Streams
Clear
Formats
Showing 1 of 1 Streams
Translating & Scaling RNA Platforms and Technologies
4:00pm - 4:30pm
Presentation: Beyond IVT: Building a Cell-Based Platform for the Next Generation of mRNA Medicines
- Conventional in vitro transcription (IVT) has enabled the first wave of mRNA products, but important challenges remain for broader therapeutic use, including dsRNA impurities, excessive immunogenicity and/or reactogenicity, repeat-dosing limitations, scalability, and supply-chain complexity.
- This presentation will introduce Sensible Biotechnologies’ cell-based platform for mRNA design, manufacturing, and scale-up, and discuss how a cell-based production approach can enable high-purity mRNA with a favorable immunogenicity profile.
- It will also explore what this could mean for the future of mRNA therapeutics, particularly in applications where repeat dosing, high purity, low immunogenicity, and strong translational performance are critical.
- Miroslav Gaparek - CEO, Sensible Biotechnologies
4:30pm - 5:00pm
Presentation: Establishing RNA Technologies in New Zealand
- Rebecca McKenzie - Project Leader RNA Platform, Malaghan Institute
5:00pm - 5:30pm
Presentation: Improving DNA template generation for high-throughput small-scale RNA production
- Jochem Vink - Development Lead RNA Platform, Ferrier Research Institute
Filter
Streams
Clear
Formats
Choose Day
