Day 2 - UTC+08:00
Delving into the transformative potential of nucleic acid-based therapies and enabling technologies, with insights into APAC’s unique investment opportunities, including emerging biotech hubs, innovative startups, and regional strengths in clinical trials and manufacturing
Exploring collaborative investment strategies to accelerate development pipelines and expand market access for nucleic acid technologies across APAC.
- Carl Firth - Partner, Panacea Capital
- Fong Ming Koh - Principal, LYFE Capital
- Yvonne Koh - Vice President, Therapeutics, ClavystBio
- Alex Mata - Equity Analyst - Healthcare, Alecta
Examining the evolving regulatory frameworks for nucleic acid therapeutics across Asia-Pacific and Western regions, with a focus on harmonizing standards to support global innovation and accessibility.
Discussing challenges and opportunities in navigating diverse regulatory landscapes, including strategies for accelerating approvals and ensuring safety and efficacy in emerging RNA-based treatments.
- Jack Wong - CEO and Founder, Asia Regulatory Professionals Association (ARPA)
- Mimi Lee - Program Manager, Opus 132
- Skin regeneration is governed by the fibroblast–extracellular matrix (ECM) axis, yet current therapies typically act indirectly on fibroblasts and yield limited or short-lived improvements in collagen content and dermal architecture.
- This presentation will discuss how RNA therapeutics can be applied in direct ECM restoration, with a particular focus on advances on trans-amplifying RNA (taRNA) technologies. It will also address current limitations of mRNA drug in regeneration medicine, and describe efforts in her group to further improve mRNA delivery, durability and functionality.
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- Qianqian Ni - Assistant Professor, National University of Singapore
- Developing a scalable cell-derived nanoparticle platform for RNA delivery to the brain
- In preclinical animal studies, the platform showed functional RNA delivery to over 70% of neurons following a single IV injection
- Luca Bolondi - CEO, Crane Biosciences
- Peter Weinstein - CEO, Vaxxirna
- Luca Bolondi - CEO, Crane Biosciences
- Tim Mercer - Director, BASE mRNA facility, The University of Queensland
- Rosalind Tan - Venture Architect, GRIP
Highlighting the future innovation potential of RNA therapeutics, focusing on next-generation approaches such as AI-driven RNA design, RNA editing, non-coding RNAs, and circular RNAs (circRNAs) to address complex diseases and advance precision medicine in Asia-Pacific. This panel will explore how artificial intelligence is revolutionizing RNA drug discovery, target identification, and optimization of therapeutic efficacy, accelerating the development of personalized RNA-based treatments.
- Muthiah (Mano) Manoharan, PhD - Senior Vice President of Drug Innovation and Distinguished Research Scientist, Alnylam Pharmaceuticals
- Mohamed ElSayed - Executive Director, NATi
- Peter Weinstein - CEO, Vaxxirna
