Key Sessions
Marie Wikstrom-Lindholm
Keynote Panel: The Potential of RNA Therapeutics – Rare vs Broad Spectrum Conditions
Silence Therapeutics
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Main Conference – Day 1 - CET (Central European Time, GMT+01:00)
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Main Conference – Day 1 - CET (Central European Time, GMT+01:00)
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Hall G2: Business Forum: Rapid-Fire Innovation Session
12:15 - 12:30
Innovation Presentation: Bispecific-siRNA silencing synergistic target genes to prevent atherosclerotic cardiovascular disease (ASCVD) and fatty liver disease
Data will be presented validating two Argonaute dual targeting siRNAs (bis-siRNAs), respectively addressing residual risk/unmet need for ASCVD, including heart attacks and stroke, and fatty liver diseases (MASLD/MASH). We will present compelling and comprehensive results from in vitro and large in vivo studies, including extensive biochemical, gene expression and metabolomics assays demonstrating the extraordinary efficacy and safety of these agents. Together a strong case will be made for pursuing clinical development of these agents with the aim of launching first in man studies in the next 12-18 months.
- Michael Khan - CEO, ARGONAUTE RNA LIMITED
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