Key Sessions
Marie Wikstrom-Lindholm
Keynote Panel: The Potential of RNA Therapeutics – Rare vs Chronic Applications
Silence Therapeutics
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Main Conference – Day 1 - CET (Central European Time, GMT+01:00)
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Main Conference – Day 1 - CET (Central European Time, GMT+01:00)
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Oligo-based Therapeutics: Targeted Delivery
16:15 - 16:45
Presentation: Effective and safe inhalation of self-assembling siRNA therapeutics for respiratory diseases
- Developing self-assembling siRNA therapeutics designed for effective and targeted delivery via inhalation to treat respiratory diseases.
- Optimizing siRNA formulations to ensure stability, efficient pulmonary uptake, and minimal off-target effects.
- Demonstrating safety and therapeutic efficacy through advanced preclinical models of respiratory disease
- Philippe Vollmer Barbosa - Project Manager, Fraunhofer
16:45 - 17:15
Presentation: Advancing Delivery Systems for Enhanced Stability, Uptake, and Precision Targeting of Oligonucleotides
- Addressing the barriers to effective transport of nucleic acid therapeutics, such as stability, cellular uptake, and tissue specificity.
- Exploring lipid nanoparticles, polymer-based carriers, and conjugate systems for precise and efficient delivery.
- Highlighting preclinical and clinical advancements in delivery technologies for nucleic acid-based therapies.
- Discussing emerging approaches, such as extracellular vesicles and targeted delivery systems, to enhance therapeutic outcomes.
- Nick Lench - Executive Director, Nucleic Acid Therapy Accelerator
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