Main Conference – Day 1Wednesday, 18 March 2026 - CET (Central European Time, GMT+01:00)

• RNA modifications play a critical role in influencing RNA structure and function, yet traditional prediction methods often fail to account for these molecular marks.
• The ViennaRNA Package introduces an advanced approach to RNA structure prediction by integrating modified nucleotides through custom alphabets, tailored energy parameters, and adapted folding algorithms.
• Experimental data on modified bases is incorporated into the prediction process, enhancing the accuracy of RNA structure modeling.
• Case studies highlight the improved prediction accuracy for known modified RNAs, demonstrating the effectiveness of this approach in addressing challenges associated with modified RNA structure analysis.

Please contact the RNA Leaders Team (Jennifer.Wickett@informa.com) if you are interested in presenting.

• Characterisation of mRNA critical quality attributes using LC MS
• Automated online direct mRNA sequencing mapping using partial RNase T1 digests
• Analysis of mRNA multimerisation (aggregation) using ion-pair reversed phase HPLC