Muthusamy Jayaraman, Ph.D.

SVP, Chemistry and Delivery at ReNAgade Therapeutics

Speaker

Dr. Muthusamy Jayaraman (MJ), Ph.D., has 25 years of drug discovery experience, with roles spanning early phase drug discovery research in small molecules, siRNA and genome editing to strategic planning and operations for clinical development. MJ is currently SVP of Chemistry and Delivery at ReNAgade Therapeutics having previously worked as Head of Non-Viral Delivery at Crispr Therapeutics. Prior to Crispr, MJ was at Alnylam Pharmaceuticals for 13 years and was instrumental in bringing first siRNA-LNP product, ONPATTRO to market. MJ played a key role in the discovery of MC3 and its development at various stages including regulatory support. A class of ionizable lipid, “Biodegradable lipids” discovered by MJ laid the foundation for all current LNP delivery technology including mRNA vaccines and Crispr/Cas09 editing delivery platform. MJ holds a PhD in Organic Chemistry from NCL, Pune, and was an NCI Postdoctoral Fellow at Purdue University.