Léo Marx, PhD

Medicinal Chemistry Project Manager at Debiopharm Research & Manufacturing

Speaker

In 2014, I obtained a PhD in Organic Chemistry in the group of Jonathan Burton , where I completed the synthesis of natural product Salinosporamide A, a potent protasome inhibitor (University of Oxford, UK)

I then carried an Industrial Postdoc in Medicinal Chemistry working on the design, optimization & conjugation of novel legumain cleavable ADC linkers carrying KSP inhibitor with Hans Georg Lerchen (Bayer Wupperal, Germany).

I joined Debiopharm in 2017 as Medicinal Chemist to work on the development of new linkers technologies and their application to novel ADC product such as Debio 1562M, which is now in phase I clinical trials for treatment of AML. I have recently taken the function of Head of ADC Research & Technologies.