Agenda for Day 3 - Wednesday 11 November, 2026Wednesday, 11 November 2026

• Explore critical lessons learned from failed and successful clinical trials

• Gain insights into improving trial design and operational processes

• Examine real world case studies to enhance future trial outcomes

• Explore how cellular therapy platforms are expanding from oncology into autoimmune diseases, leveraging translational and clinical insights across therapeutic areas

• Review the evolving clinical and study landscape, including emerging efficacy and safety data across oncology and autoimmune indications, and discuss lessons learned for future development strategies

• Examine how benefit–risk expectations, endpoints, regulatory considerations, and development paradigms fundamentally change when moving from oncology into chronic autoimmune diseases

• Address organizational challenges of working across multiple departments with different priorities and stakeholder expectations, including governance, resource allocation, manufacturing considerations, and portfolio prioritization

• Learn how to engage CROs as part of the team

• Minimize risks and enhance clinical trial partnerships

• Building relationships between vendors and biotech companies

• Explore bold and innovative strategies for Phase 3 trials in rare diseases, focusing on risk-taking and challenging existing literature to achieve groundbreaking results.

• Learn how to design clinical trials that differentiate first-in-class therapeutics and position novel therapies for success.

• Discover adaptive, platform, and basket trial designs to enhance efficiency and accelerate the development of breakthrough therapies

• Explore financial barriers in clinical trials and their impact on operations

• Discuss cost-saving strategies and innovative approaches to streamline trial processes

• Highlight mission driven investments that balance capital and clinical impact

• Discover how AI streamlines clinical trial operations- from intelligent protocol development and patient recruitment to digital twin technology that reduces patient requirements while maintaining regulatory compliance

• Learn strategies for shifting from traditional site-centric approaches to patient-focused trial designs that improve accessibility, diversity, and retention through decentralized and hybrid methodologies

• Explore real-world case studies and expert predictions on AI's future impact in precision medicine, regulatory evolution, and the transformation of clinical research operations