Agenda March 18, 2027: Main Conference Day TwoThursday, 18 March 2027 - PT (Pacific Time, GMT-08:00)

• Apply bioprocess engineering and process understanding to enable a lower-cost resin substitution without fundamentally changing the licensed process or product characteristics.
• Use qualified small-scale models and a risk-based CMC strategy to streamline comparability, qualification, and validation.
• Achieve successful commercial scale PPQ while maintaining process robustness, product quality, and supply continuity.

This talk explores the purification of increasingly complex multispecific biotherapeutics. Purification scientists face challenges in finding scalable, efficient methods as therapies advance. Capture redox adds a powerful technique to the purification toolkit, enabling the generation of multispecific antibodies through electro-steering heterodimerization during affinity chromatography—streamlining production and supporting the next generation of innovative medicines.