San Diego Convention Center,
San Diego, CA, USA
Cell Line Development & Engineering Track
Developing high-performing, stable, and scalable cell lines is a cornerstone of modern biologics manufacturing. With modalities becoming more complex and timelines shorter, integrating advanced engineering, AI-driven selection, and early process alignment is key.
Designing the Foundation for Speed, Stability, and Scalability - Key Topics Driving Innovation in Cell Line Development & Engineering:
AI & Predictive Modelling
Discover how artificial intelligence, predictive modelling, and big-data analytics are transforming the way cell lines are designed, screened, and optimised. Learn how leading innovators are using digital tools to predict productivity, enhance quality, and accelerate decision-making across bioprocess development.
Host Cell Engineering & Vector Innovation
Designing next-gen hosts and vectors is critical for producing complex multi-specific biologics efficiently. Dive into the latest advances in host cell platforms, gene editing, and expression vector optimisation that enable consistent, high-performing cell lines for complex biologics and bispecifics. Sessions will reveal how next-generation engineering strategies are delivering higher yields, improved stability, and greater flexibility for emerging therapeutic formats.
Speed to Clinic & Process Integration
Hear how leading organisations are overcoming traditional bottlenecks to compress cell line development timelines and ensure smooth, reliable scale-up to GMP manufacturing. Focusing on early integration between CLD and process development, risk mitigation, and platform approaches that bring therapies to patients faster.
Automation & Efficiency in Screening
High-throughput and automated screening is revolutionizing clone selection, enabling faster, more reproducible results and improving decision-making in early-stage CLD. Learn how integrated digital workflows and automated analytics are increasing reproducibility, speed, and productivity across the cell line development pipeline.
Cell Line Development & Engineering Speaker Snapshot
FAQs
What is the focus of the Cell Line Development track at BPI West?
The Cell Line Development track at BPI West explores cutting-edge strategies and technologies to optimize cell line engineering, productivity, and stability. It emphasizes integrating AI, automation, and high-throughput screening to accelerate biopharmaceutical development.
What are the key industry trends in cell line development discussed at BPI West?
Key trends include:
- AI-driven tools for cell line optimization and predictive modeling.
- Advances in CRISPR/Cas9 and other gene-editing technologies.
- High-density CHO cell cultures as alternatives to traditional perfusion methods.
- Automation and robotics for streamlining workflows.
- Digital twins for quality prediction and process control.
How does AI impact cell line development in biopharmaceuticals?
AI is transforming cell line development by enabling faster identification of high-performing clones, improving process control, and enhancing quality prediction through digital twins. Sessions at BPI West highlight real-world applications of AI in biomanufacturing.
What challenges in cell line development are addressed at BPI West?
The agenda addresses challenges such as:
- Ensuring genetic stability and reproducibility.
- Overcoming bottlenecks in scalability and productivity.
- Meeting regulatory requirements for cell line characterization.
- Managing variability in cell line performance.
What technologies are highlighted in the Cell Line Development agenda?
Highlighted technologies include:
- CRISPR/Cas9 for precise gene editing.
- High-throughput screening platforms for clone selection.
- Digital twins for process optimization.
- Automation and robotics for enhanced efficiency.
How does the Cell Line Development track address regulatory compliance?
Sessions focus on strategies for meeting regulatory requirements, including:
- Best practices for cell line characterization and traceability.
- Navigating global regulatory frameworks for biologics.
- Ensuring compliance with evolving industry standards.
What are the benefits of attending the Cell Line Development track?
Attendees will gain:
- Insights into emerging trends and technologies.
- Practical solutions to common challenges in cell line development.
- Networking opportunities with industry leaders and experts.
- Access to case studies and real-world applications.
How can I stay updated on cell line development trends?
Follow industry publications such as our media partner, BioProcess International, a leading resource for biopharmaceutical insights and innovations.