San Diego Convention Center,
San Diego, CA, USA
Cell Line Development & Engineering Track
Developing high-performing, stable, and scalable cell lines is a cornerstone of modern biologics manufacturing. With modalities becoming more complex and timelines shorter, integrating advanced engineering, AI-driven selection, and early process alignment is key.
Designing the Foundation for Speed, Stability, and Scalability - Key Topics Driving Innovation in Cell Line Development & Engineering:
AI & Predictive Modelling
Discover how artificial intelligence, predictive modelling, and big-data analytics are transforming the way cell lines are designed, screened, and optimised. Learn how leading innovators are using digital tools to predict productivity, enhance quality, and accelerate decision-making across bioprocess development.
Host Cell Engineering & Vector Innovation
Designing next-gen hosts and vectors is critical for producing complex multi-specific biologics efficiently. Dive into the latest advances in host cell platforms, gene editing, and expression vector optimisation that enable consistent, high-performing cell lines for complex biologics and bispecifics. Sessions will reveal how next-generation engineering strategies are delivering higher yields, improved stability, and greater flexibility for emerging therapeutic formats.
Speed to Clinic & Process Integration
Hear how leading organisations are overcoming traditional bottlenecks to compress cell line development timelines and ensure smooth, reliable scale-up to GMP manufacturing. Focusing on early integration between CLD and process development, risk mitigation, and platform approaches that bring therapies to patients faster.
Automation & Efficiency in Screening
High-throughput and automated screening is revolutionizing clone selection, enabling faster, more reproducible results and improving decision-making in early-stage CLD. Learn how integrated digital workflows and automated analytics are increasing reproducibility, speed, and productivity across the cell line development pipeline.
FAQs
What is the focus of the Cell Line Development track at BPI West?
The Cell Line Development track at BPI West explores cutting-edge strategies and technologies to optimize cell line engineering, productivity, and stability. It emphasizes integrating AI, automation, and high-throughput screening to accelerate biopharmaceutical development.
What are the key industry trends in cell line development discussed at BPI West?
Key trends include:
- AI-driven tools for cell line optimization and predictive modeling.
- Advances in CRISPR/Cas9 and other gene-editing technologies.
- High-density CHO cell cultures as alternatives to traditional perfusion methods.
- Automation and robotics for streamlining workflows.
- Digital twins for quality prediction and process control.
How does AI impact cell line development in biopharmaceuticals?
AI is transforming cell line development by enabling faster identification of high-performing clones, improving process control, and enhancing quality prediction through digital twins. Sessions at BPI West highlight real-world applications of AI in biomanufacturing.
What challenges in cell line development are addressed at BPI West?
The agenda addresses challenges such as:
- Ensuring genetic stability and reproducibility.
- Overcoming bottlenecks in scalability and productivity.
- Meeting regulatory requirements for cell line characterization.
- Managing variability in cell line performance.
What technologies are highlighted in the Cell Line Development agenda?
Highlighted technologies include:
- CRISPR/Cas9 for precise gene editing.
- High-throughput screening platforms for clone selection.
- Digital twins for process optimization.
- Automation and robotics for enhanced efficiency.
How does the Cell Line Development track address regulatory compliance?
Sessions focus on strategies for meeting regulatory requirements, including:
- Best practices for cell line characterization and traceability.
- Navigating global regulatory frameworks for biologics.
- Ensuring compliance with evolving industry standards.
What are the benefits of attending the Cell Line Development track?
Attendees will gain:
- Insights into emerging trends and technologies.
- Practical solutions to common challenges in cell line development.
- Networking opportunities with industry leaders and experts.
- Access to case studies and real-world applications.
How can I stay updated on cell line development trends?
Follow industry publications such as our media partner, BioProcess International, a leading resource for biopharmaceutical insights and innovations.