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Main Conference Day 1 (28th April 2026) - CET/CEST (Cent Europe Summer, GMT+2)
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Main Conference Day 1 (28th April 2026) - CET/CEST (Cent Europe Summer, GMT+2)
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Downstream Processing
08:55 - 09:00
Chairperson's Opening Remarks
09:00 - 09:30
Towards Platform Processes in Downstream Processing of Viral Gene Therapy Vectors
- Alois Jungbauer - Professor, Dept. of Biotechnology, University of Natural Resources and Applied Life Sciences
09:30 - 10:00
CASE STUDY: Tackling Instability in ADC purification - Minimising Aggregation and Free Drug Payload
Strategies to overcome the unique stability challenges in ADC purification
Optimising purification steps to maintain integrity of conjugate
Preventing aggregation
Efficiently removing cytotoxic free drug payloads to ensure patient safety.
Showing 1 of 1 Streams
Downstream Processing
11:15 - 11:45
Using High-Throughput Process Development (HTPD) to Design Bespoke Purification Processes
How can miniaturised formats and robotics accelerate the design of novel purification processes?
Utilising HTPD to:
Rapidly screen conditions in parallel
Accelerate development cycle for non-platform molecules
11:45 - 12:15
PANEL DISCUSSION: Emerging Purification Strategies for Extracellular Vesicles (EVs) and Exosomes
EVs are rapidly growing, but with no established purification platform
Current state-of-the-art purification strategies
Pros and Cons of differing approaches:
Centrifugation
Filtration
Chromatography
The future of EV purification: what will a platform look like?
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